Article

The landscape of human brain immune response in patients with severe COVID-19

2021-01-11

Abstract excerpt

In coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the relationship between brain tropism, neuroinflammation and host immune response has not been well characterized. We analyzed 68,557 single-nucleus transcriptomes from three brain regions (dorsolateral prefrontal cortex, medulla oblongata and choroid plexus) and identified an increased propor...

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Literature Corpus work: 9732eace-8dbd-5ac6-8741-832695937c27
DOI: 10.1101/2021.01.08.425999

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