Article

Opposing transcriptomic gradients explain orthogonal maps in human visual areas

2019-10-21

Abstract excerpt

Opposing transcriptomic gradients explain the large-scale organization of cortex. Here, we show that opposing transcriptomic gradients also explain the fine-scale organization of orthogonal maps in human visual areas. We propose a model relating transcriptomics, cell density, and function, which predicts that specific cortical locations within these visual maps are microanatomically distinct and differentially sus...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 96e856ad-3b79-5724-889d-af26bc7af7e0
DOI: 10.1101/812560

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Opposing transcriptomic gradients explain orthogonal maps in human visual areasDOI 10.1101/812560Read

Human visual cortex is organized along two genetically opposed hierarchical gradients with unique developmental and evolutionary originsSemantic proximity Read

Deciphering cell type-specific causal genetic effects on brain imaging-derived phenotypes and disorders with single-cell Mendelian randomization.Semantic proximity Read

Transcriptomic cytoarchitecture reveals principles of human neocortex organizationSemantic proximity Read

Conserved whole-brain spatiomolecular gradients shape adult brain functional organizationSemantic proximity Read

LaminaRGeneVis: a tool to visualize gene expression across the laminar architecture of the human neocortexSemantic proximity Read

Single-cell in situ transcriptomic map of astrocyte cortical layer diversitySemantic proximity Read

Single-Cell Atlas Uncovers Layer 4 Heterogeneity and Functional Gradients in Rhesus Macaque Visual CortexSemantic proximity Read

Transcriptomic contributions to a modern cytoarchitectonic parcellation of the human cerebral cortexSemantic proximity Read

Charting the Spatial Transcriptome of the Human Cerebral Cortex at Single-Cell ResolutionSemantic proximity Read

Planar cell polarity pathway and development of the human visual cortexSemantic proximity Read

Benchmarking macaque brain gene expression for horizontal and vertical translationSemantic proximity Read

The transcriptomic architecture of the human cerebral cortexSemantic proximity Read