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Inner limiting Membrane Peel Extends <i>In vivo</i> Calcium Imaging of Retinal Ganglion Cell Activity Beyond the Fovea in Non-Human Primate

2024-06-02

Abstract excerpt

<h4>Purpose</h4> Adaptive Optics Scanning Light Ophthalmoscopy (AOSLO) paired with intravitreal injection of a viral vector coding for the calcium indicator GCaMP has enabled visualization of neuronal activity in retinal ganglion cells (RGCs) at single cell resolution in the living eye. However, the inner limiting membrane (ILM) restricts viral transduction to the fovea in humans and non-human primates (NHP), hin...

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Literature Corpus work
96e6125b-ac49-5cf3-8a0f-0ade3e8b7785
DOI
10.1101/2024.06.02.597041
Open publication

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Inner limiting Membrane Peel Extends <i>In vivo</i> Calcium Imaging of Retinal Ganglion Cell Activity Beyond the Fovea in Non-Human PrimateDOI 10.1101/2024.06.02.597041
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