Article

Development of an image-guided non-vitrectomy subretinal access approach for trans-scleral cell and gene therapy delivery

2025-03-01

Abstract excerpt

<h4>Purpose</h4> Regenerative therapies for retinal diseases include cell and gene therapy modalities that are targeted to the subretinal space. Several recent clinical trials have shown that the morbidity of surgical access is the major limitation of safe subretinal space delivery. We aimed to develop an image-guided procedure for minimally invasive subretinal access (MISA) as a platform to deliver therapeutic a...

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Literature Corpus work: 95e61055-09b0-57f9-9ef1-aab86b21da49
DOI: 10.1101/2025.02.25.640217

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