Article
Computational modeling of human genetic variants in mice
2025-02-24
Abstract excerpt
Mouse models represent a powerful platform to study genes and variants associated with human diseases. While genome editing technologies have increased the rate and precision of model development, predicting and installing specific types of mutations in mice that mimic the native human genetic context is complicated. Computational tools can identify and align orthologous wild-type genetic sequences from different...
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Identifiers and source
- Literature Corpus work
- 96e38c0b-bbfa-5646-b6eb-252220295493
- DOI
- 10.1101/2025.02.23.639784