Article

COMPENSATION FOR CHRONIC OXIDATIVE STRESS IN ALADIN NULL MICE

2017-07-17

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Mutations in the AAAS gene coding for the nuclear pore complex protein ALADIN lead to the autosomal recessive disorder triple A syndrome. Triple A patients present with a characteristic phenotype including alacrima, achalasia and adrenal insufficiency. Patient fibroblasts show increased levels of oxidative stress and several in vitro studies demonstrated that the nucleopor...

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Literature Corpus work: 96b5da67-7b41-58fd-99e3-ab91cb811b0a
DOI: 10.1101/164442

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