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The Role of the CAG Repeat Polymorphism in the Androgen Receptor Gene and of Skewed X-Chromosome Inactivation, in the Pathogenesis of Hirsutism

2000-04-01

Abstract excerpt

The human androgen receptor (AR) gene contains a variable number of CAG repeats within exon 1. Shorter AR alleles, by increasing transactivation, may result in augmented AR-mediated sensitivity of the hair follicle.We have evaluated whether the number of CAG repeats, or if skewed inactivation of X-chromosome, favoring the presence of shorter AR alleles, influence hirsutism in women with and without hyperandrogenem...

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Literature Corpus work
96477102-0a61-5bb8-bd4a-b74e4e1b99dd
DOI
10.1210/jc.85.4.1735
Open publication

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The Role of the CAG Repeat Polymorphism in the Androgen Receptor Gene and of Skewed X-Chromosome Inactivation, in the Pathogenesis of HirsutismDOI 10.1210/jc.85.4.1735
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