Article
The role of androgen receptor activity mediated by the CAG repeat polymorphism in the pathogenesis of PCOS.
Journal of medicine and life - 15 Mar 2013
Baculescu N
Abstract excerpt
Polycystic ovary syndrome (PCOS), one of the most common and complex endocrine disorders affecting up to 15 % of reproductive age women, is considered a predominantly hyperandrogenic syndrome according to the Androgen Excess Society. It is generally accepted that androgens determine the characteristic features of PCOS; in this context, a hyperactive androgen receptor (AR) at the levels of the GnRH pulse generator...
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