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Androgen Receptor Gene CAG Repeat Polymorphism and X-Chromosome Inactivation in Children with Premature Adrenarche

6 Feb 2008

Abstract excerpt

CONTEXT: There is variation in the adrenal androgen levels and clinical findings of children with premature adrenarche (PA). OBJECTIVES: We hypothesized that androgen sensitivity, indicated by the length of CAG repeat in the X-chromosomal androgen receptor (AR) gene has a role in the polygenic pathogenesis of PA. DESIGN AND PATIENTS: We performed a cross-sectional association study among 73 Finnish Caucasian...

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PMID: 18252782
DOI: 10.1210/jc.2007-2707

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