Article
Proteomic Profile of TGF-β1 treated Lung Fibroblasts identifies Novel Markers of Activated Fibroblasts in the Silica Exposed Rat Lung
2018-10-01
Abstract excerpt
<h4>ABSTRACT</h4> We performed liquid chromatography-tandem mass spectrometry (LC-MS/MS) on control and TGF-β1-exposed rat lung fibroblasts to identify proteins differentially expressed between cell populations. A total of 1648 proteins were found to be differentially expressed in response to TGF-β1 treatment and 196 proteins were expressed at ≥ 1.2 fold relative to control. Guided by these results, we next deter...
Topics
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- Cancer-related molecular mechanisms research
- Galectins and Cancer Biology
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Medical Imaging and Pathology Studies
- Occupational and environmental lung diseases
- Occupational exposure and asthma
- Studies on Chitinases and Chitosanases
- Systemic Sclerosis and Related Diseases
Identifiers and source
- Literature Corpus work
- 960f6d7d-5fc1-5916-b04e-748a1190b590
- DOI
- 10.1101/431825
