Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of transforming growth factor-beta-regulated microRNAs and the microRNA-targetomes in primary lung fibroblasts

14 Sept 2017

Abstract excerpt

BACKGROUND: Lung fibroblasts are involved in extracellular matrix homeostasis, which is mainly regulated by transforming growth factor-beta (TGF-β), and are therefore crucial in lung tissue repair and remodeling. Abnormal repair and remodeling has been observed in lung diseases like COPD. As miRNA levels can be influenced by TGF-β, we hypothesized that TGF-β influences miRNA expression in lung fibroblasts,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Obstructive Pulmonary Disease (COPD) Research
Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to MicroRNA in disease regulation

Source

Identifiers

PMID: 28910321
DOI: 10.1371/journal.pone.0183815

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of transforming growth factor-beta-regulated microRNAs and the microRNA-targetomes in primary lung fibroblastsPMID 28910321Read ↗

Lung fibroblasts express a miR-19a-19b-20a sub-cluster to suppress TGF-β-associated fibroblast activation in murine pulmonary fibrosisSemantic proximity Read ↗

Role of MicroRNAs in TGF-β Signaling Pathway-Mediated Pulmonary FibrosisSemantic proximity Read ↗

MicroRNAs as potential targets for progressive pulmonary fibrosisSemantic proximity Read ↗

Systems Analysis of Transcriptomic and Proteomic Profiles Identifies Novel Regulation of Fibrotic Programs by miRNAs in Pulmonary Fibrosis FibroblastsSemantic proximity Read ↗

The Role of miRNAs in Extracellular Matrix Repair and Chronic Fibrotic Lung DiseasesSemantic proximity Read ↗

Construction of a TFs-miRNA-mRNA network related to idiopathic pulmonary fibrosisSemantic proximity Read ↗

miR-130b-3p Modulates Epithelial-Mesenchymal Crosstalk in Lung Fibrosis by Targeting IGF-1Semantic proximity Read ↗

MiRNA, a New Treatment Strategy for Pulmonary FibrosisSemantic proximity Read ↗

MicroRNA regulatory networks in idiopathic pulmonary fibrosisSemantic proximity Read ↗

Bulk RNA-Sequencing of small airway cell cultures from IPF and post-COVID lung fibrosis patients illustrates disease signatures and differential responses to TGF- <i>β</i> 1 treatmentSemantic proximity Read ↗

Role of MicroRNAs in Signaling Pathways Associated with the Pathogenesis of Idiopathic Pulmonary Fibrosis: A Focus on Epithelial-Mesenchymal TransitionSemantic proximity Read ↗

Systems biology of interstitial lung diseases: integration of mRNA and microRNA expression changesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.