Article

Collagen VI regulates motor circuit plasticity and motor performance by cannabinoid modulation

2021-09-05

Abstract excerpt

<h4>ABSTRACT</h4> Collagen VI is a key component of muscle basement membranes, and genetic variants can cause monogenic muscular dystrophies. Conversely, human genetic studies recently implicated collagen VI in central nervous system function, with variants causing the movement disorder dystonia. To elucidate the neurophysiological role of collagen VI, we generated mice with a truncation of the dystonia-related c...

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Literature Corpus work: 95ebd897-de87-5e79-9383-8540188dd696
DOI: 10.1101/2021.09.03.458830

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