Article
Synaptic basal lamina-associated congenital myasthenic syndromes.
Annals of the New York Academy of Sciences - 1 Dec 2012
Maselli Ricardo A, Arredondo Juan, Ferns Michael J, Wollmann Robert L
Abstract excerpt
Proteins associated with the basal lamina (BL) participate in complex signal transduction processes that are essential for the development and maintenance of the neuromuscular junction (NMJ). Most important junctional BL proteins are collagens, such as collagen IV (α3-6), collagen XIII, and ColQ; laminins; nidogens; and heparan sulfate proteoglycans, such as perlecan and agrin. Mice lacking Colq (Colq(-/-)),...
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