Article

Case Report: Acute isoniazid intoxication after intentional ingestion

2022-08-22

Abstract excerpt

Isoniazid is an anti-tuberculosis medication that is extensively used for treatment and prevention of tuberculosis. Acute isoniazid poisoning is characterized by a clinical triad of recurrent seizures, raised anion gap metabolic acidosis and coma. The seizures are unresponsive to standard anticonvulsant drugs, instead requiring pyridoxine administered in a dose equal to the amount of isoniazid consumed. Due to the...

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Literature Corpus work: 959ff597-0204-5530-9eaf-15e9e60c8f1e
DOI: 10.12688/wellcomeopenres.18068.1

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