Article
PDHB: A gene associated with Cuproptosis and encoding the beta subunit of pyruvate dehydrogenase is involved in the oxidative decarboxylation reaction.
2024-12-11
Abstract excerpt
Cuproptosis is a regulated cell death mechanism that has recently been identified and is distinct from other known cell death mechanisms (e.g. apoptosis, Ferroptosis, necrotic apoptosis……). Cuproptosis causes oligomer formation through the abnormal accumulation of intracellular copper ions that target binding to the thioctylated protein component of the tricarboxylic acid cycle. At the same time, it can destabilis...
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Identifiers and source
- Literature Corpus work
- 950bfd56-c362-57d1-8bd1-cf596f55f849
- DOI
- 10.22541/au.173389519.97975576/v1
