Back to search

Article

PDHB: A gene associated with Cuproptosis and encoding the beta subunit of pyruvate dehydrogenase is involved in the oxidative decarboxylation reaction.

2024-12-11

Abstract excerpt

Cuproptosis is a regulated cell death mechanism that has recently been identified and is distinct from other known cell death mechanisms (e.g. apoptosis, Ferroptosis, necrotic apoptosis……). Cuproptosis causes oligomer formation through the abnormal accumulation of intracellular copper ions that target binding to the thioctylated protein component of the tricarboxylic acid cycle. At the same time, it can destabilis...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
950bfd56-c362-57d1-8bd1-cf596f55f849
DOI
10.22541/au.173389519.97975576/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
PDHB: A gene associated with Cuproptosis and encoding the beta subunit of pyruvate dehydrogenase is involved in the oxidative decarboxylation reaction.DOI 10.22541/au.173389519.97975576/v1
Select a neighboring publication to make it the new centre.