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Cuproptosis-related genes and agents: implications in tumor drug resistance and future perspectives

8 May 2025

Abstract excerpt

In the field of tumor treatment, drug resistance remains a significant challenge requiring urgent intervention. Recent developments in cell death research have highlighted cuproptosis, a mechanism of cell death induced by copper, as a promising avenue for understanding tumor biology and addressing drug resistance. Cuproptosis is initiated by the dysregulation of copper homeostasis, which in turn triggers...

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PMID: 40406488
DOI: 10.3389/fphar.2025.1559236

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