Article

Direct exposure to SARS-CoV-2 and cigarette smoke increases infection severity and alters the stem cell-derived airway repair response

2020-07-29

Abstract excerpt

<h4>SUMMARY</h4> Most demographic studies are now associating current smoking status with increased risk of severe COVID-19 and mortality from the disease but there remain many questions about how direct cigarette smoke exposure affects SARS-CoV-2 airway cell infection. We directly exposed mucociliary air-liquid interface (ALI) cultures derived from primary human nonsmoker airway basal stem cells (ABSCs) to short...

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Literature Corpus work: 95050f8d-aa96-57ad-83a1-c3d201b5c60c
DOI: 10.1101/2020.07.28.226092

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