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Article

Role of NLRP3 Inflammasome on Different Phenotypes of Chronic Rhinosinusitis.

American journal of rhinology & allergy - 1 Sept 2022

Yang Yang, Chen Haihong, Zhong Jiangtao, Shen Lifang, Zheng Xiu

Abstract excerpt

BACKGROUND: The pathophysiologic mechanisms of human chronic rhinosinusitis (CRS) are highly complex, and sinonasal colonization with pathogens is the first and most important step in this process. NLRP3, the main receptor activated by pathogen-associated molecular patterns (PAMPs), is associated with a variety of inflammatory diseases, including airway inflammation; however, the understanding of its role in CRS...

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Identifiers

PMID: 35746845
DOI: 10.1177/19458924221101218

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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