Article

Personalized Inhaler Selection in COPD and Asthma: Clinical Implications of Aerosol Characteristics and Device Performance

2026-03-18

Abstract excerpt

The management of chronic obstructive pulmonary disease (COPD) and asthma depends critically on the effective delivery of aerosolized medications to the respiratory tract. Clinical efficacy is determined not only by the active pharmaceutical ingredient but also by a complex interplay among drug formulation, aerosol particle size, inhaler device characteristics, dosing frequency, and patient-specific factors. This...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 94e3624b-08fe-566a-a306-92e068830092
DOI: 10.20944/preprints202603.1453.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Personalized Inhaler Selection in COPD and Asthma: Clinical Implications of Aerosol Characteristics and Device PerformanceDOI 10.20944/preprints202603.1453.v1Read

Towards More Precise Targeting of Inhaled Aerosols to Different Areas of the Respiratory SystemSemantic proximity Read

Clinical Implications of Peak Inspiratory Flow in COPD: Post Hoc Analyses of the TRONARTO Study.Semantic proximity Read

Assessing drug deposition efficacies, environmental impact and affordability for inhalers among chronic respiratory diseases: A systematic reviewSemantic proximity Read

Computational Fluid Particle Dynamics-Informed Machine Learning Prototype for a User-Centered Smart Inhaler Enabling Uniform Drug Delivery to Small AirwaysSemantic proximity Read

Experimental Evaluation of Dry Powder Inhalers During In- and Exhalation Using a Model of the Human Respiratory System (xPULM™)Semantic proximity Read

Computational Fluid Particle Dynamics (CFPD)-Based Virtual Next Generation Impactor (vNGI) to Predict the Aerodynamic Particle Size Distribution (APSD) of Respiratory Drug Delivery Products: Toward New Approach Methodologies (NAMs) in Inhaler Performance EvaluationSemantic proximity Read

Intranasal and Pulmonary Lipid Nanoparticles for Gene Delivery: Turning Challenges into OpportunitiesSemantic proximity Read

Site-Specific Microparticle Inhalation Therapy: A New Approach to Nasopharyngeal SymptomsSemantic proximity Read

Respiratory healthcare by design: Computational approaches bringing respiratory precision and personalised medicine closer to bedside.Semantic proximity Read

Advancements in Drug Delivery Systems from Chewable Tablets to NanomedicineSemantic proximity Read

Eulerian–Lagrangian and thin film modeling of drug delivery under physiologically varying breathing in a realistic lung modelSemantic proximity Read

Dose Emission and Aerodynamics Characterization of Tiotropium Particles Are Influenced by the Inhalation Rate and Number of Inhalations Per Inhaler DoseSemantic proximity Read