Article

A Population-level Strain Genotyping Method to Study Pathogen Strain Dynamics in Human Infections

2021-07-03

Abstract excerpt

A hallmark of chronic bacterial infections is the long-term persistence of one or more pathogen species at the compromised site. Repeated detection of the same bacterial species can suggest that a single strain or lineage is continually present. However, infection with multiple strains of a given species, strain acquisition and loss, and changes in strain relative abundance can occur. Detecting strain-level change...

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Literature Corpus work: 94607b23-f1bc-58b6-8521-e81ba8ab67e6
DOI: 10.1101/2021.07.02.450905

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