Article
Human prion diseases.
Current opinion in neurology - 1 Aug 1995
Parchi P, Gambetti P
Abstract excerpt
Major advances have been made in prion diseases. Recent data indicate that the prion protein is likely to be a synaptic protein with a functional role in synaptic transmission. An impressive body of evidence suggests that (1) the normal prion protein plays a central role in prion replication; (2) the replication process implies an interaction between the normal prion protein and the pathogenic prion protein; and...
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