Article
Human prion diseases.
Current opinion in neurology - 1 Aug 1995
Parchi P, Gambetti P
Abstract excerpt
Major advances have been made in prion diseases. Recent data indicate that the prion protein is likely to be a synaptic protein with a functional role in synaptic transmission. An impressive body of evidence suggests that (1) the normal prion protein plays a central role in prion replication; (2)...
Topics
- Adult
- Aged
- Animals
- Dementia
- Female
- Genotype
- Humans
- Male
- Mice
- Mice, Transgenic
- Middle Aged
- Phenotype
- Prion Diseases
- Prions
- Synaptic Transmission