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A stemness-based eleven-gene signature correlates with the clinical outcome of hepatocellular carcinoma

19 Jun 2021

Abstract excerpt

BACKGROUND: Cumulative evidences have been implicated cancer stem cells in the tumor environment of hepatocellular carcinoma (HCC) cells, whereas the biological functions and prognostic significance of stemness related genes (SRGs) in HCC is still unclear. METHODS: Molecular subtypes were identified by cumulative distribution function (CDF) clustering on 207 prognostic SRGs. The overall survival (OS) predictive...

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PMID: 34147074
DOI: 10.1186/s12885-021-08351-0

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