Article
Evidence for, and taxonomic value of, an arachidonic acid cascade in the Lipomycetaceae.
Antonie van Leeuwenhoek - 1 Nov 1992
Kock J L, Coetzee D J, van Dyk M S, Truscott M, Botha A, Augustyn O P
Abstract excerpt
By using specific inhibitors of the lipoxygenase and cyclo-oxygenase pathways, arachidonic acid metabolites with similar sensitivities towards these inhibitors as in humans, were detected in Dipodascopsis uninucleata. The taxonomic value of aspirin sensitive arachidonic acid metabolites in the Lipomycetaceae was next assessed. No metabolites of which the production is inhibited by aspirin were detected in strains...
Topics
- Arachidonic Acid
- Aspirin
- Fatty Acids
- Humans
- Karyotyping
- Lipoxygenase Inhibitors
- Phenotype
- Phylogeny
- Prostaglandin-Endoperoxide Synthases
- Saccharomycetales