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Soluble Urokinase Plasminogen Activator Receptor and Sirtuin 1 as Biomarkers of Disease Severity and Progression in Children with Chronic Kidney Disease​

2026-07-31

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> : Cardiovascular (CV) disease is the leading cause of morbidity and mortality in children with chronic kidney disease (CKD), driven by systemic inflammation and endothelial dysfunction. Soluble urokinase plasminogen activator receptor (suPAR) and Sirtuin 1 (SIRT1) are promising biomarkers of these pathways, but their utility in pediatric CKD, particularly in r...

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Literature Corpus work
937bf197-6b05-589a-bf28-d9bc8e2b1ea5
DOI
10.21203/rs.3.rs-10498874/v1
Open publication

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