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Integrated analysis of single-cell and bulk RNA sequencing predicts prognosis and therapeutic response using malignant epithelial cells marker genes in bladder cancer

2024-04-05

Abstract excerpt

<title>Abstract</title> <p>Bladder cancer remains a prevalent malignancy of the urinary system, closely tied to aberrations in bladder epithelial tissue. To better understand its complexities, this study delved into single-cell data to identify key marker genes of malignant cells. Subsequent analyses uncovered significant pathways facilitating intercellular communication, including COLLAGEN, PTN, and MK pathways....

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Literature Corpus work
936c873b-1578-580c-8602-3020a48df122
DOI
10.21203/rs.3.rs-4142335/v1
Open publication

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Integrated analysis of single-cell and bulk RNA sequencing predicts prognosis and therapeutic response using malignant epithelial cells marker genes in bladder cancerDOI 10.21203/rs.3.rs-4142335/v1
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