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Molecular dynamic simulation suggests stronger in-silico docking of Omicron spike on ACE2 than Wild but weaker than Delta SARS-CoV-2 variants can be blocked by engineered S1-RBD fraction

2022-06-09

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>The SARS-CoV-2 claimed millions lives globally. Occurring from Wuhan (Wild-type) in December, 2019, it constantly mutated to Omicron (B.1.1.529) the predecessor to Delta. <bold>Objectives:</bold> Omicron having ~32 spike-mutations has variable infectivity-multiplicity-immunoinvasive properties. Understanding of its mutational-effect on ACE2-binding/disease-sever...

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Literature Corpus work: 933cf5fd-b949-54ba-98f3-a4d460ff6a9a
DOI: 10.21203/rs.3.rs-1451089/v1

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