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Molecular informatics indicates better binding-energetic of Delta variant (B.1.617.2) with ACE2 than wild, D614G or N501Y CoV-2 is fully blocked by 84 amino-acid cut of wild CoV-2 spike.

2024-01-31

Abstract excerpt

The B.1.617.2 known as Delta-variant harbored diverse Spike-mutations. It is more transmissible than other (wild/D614G/N501Y) with developed immune-evasion mechanism. Currently, the binding-affinity of these variant spikes with human lung-ACE2 was evaluated aiming at some preventive/therapeutic strategies. Structure of spike-variants were retrieved from PDB/GISAID and used for homology-modeling (SWISS-MODEL). Diff...

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Literature Corpus work
856d621c-aa92-506e-a137-d92933c91648
DOI
10.22541/au.170667665.59302691/v1
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Molecular informatics indicates better binding-energetic of Delta variant (B.1.617.2) with ACE2 than wild, D614G or N501Y CoV-2 is fully blocked by 84 amino-acid cut of wild CoV-2 spike.DOI 10.22541/au.170667665.59302691/v1
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