Article

Sodium Thiosulfate: An Innovative Multi-Target Repurposed Treatment Strategy for Late-Onset Alzheimer’s Disease

2024-12-10

Abstract excerpt

Late-onset Alzheimer’s disease (LOAD) is a chronic, multifactorial, and progressive neurodegenerative disease that associates with aging and is highly prevalent in our older population (≥ 65 years of age). This hypothesis generating narrative review will examine the important role for the use of sodium thiosulfate (STS) as a possible multi-targeting treatment option for LOAD. Sulfur is widely available in...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 92e438b9-52a0-5b15-a108-d81488f2ca59
DOI: 10.20944/preprints202412.0776.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Sodium Thiosulfate: An Innovative Multi-Target Repurposed Treatment Strategy for Late-Onset Alzheimer’s DiseaseDOI 10.20944/preprints202412.0776.v1Read

Discovery of novel thiosemicarbazone-acridine targeting butyrylcholinesterase with antioxidant, metal complexing and neuroprotector abilities as potential treatment of Alzheimer's disease: In vitro, in vivo, and in silico studiesSemantic proximity Read

Copper: From enigma to therapeutic target for neurological disorderSemantic proximity Read

An Interactive Review on the Role of Tocotrienols in the Neurodegenerative DisordersSemantic proximity Read

Homocysteic Acid Causes Alzheimerʹs Disease, Promotes Cancer Growth, and Induces Various Aging ProcessesSemantic proximity Read

Therapeutic Potential of Adipose-Derived Mesenchymal Stem Cells (Admscs) and/or Taurine in Aluminum Chloride-Induced Alzheimer's Disease Rat ModelSemantic proximity Read

Copper-containing ROS-scavenging nanozyme paradoxically drives α-synucleinopathy by amplifying nitrosative stressSemantic proximity Read

The Role of Copper in Alzheimer’s Disease Etiopathogenesis: An Updated Systematic ReviewSemantic proximity Read

Selenium-based compounds: Emerging players in the ever-unfolding story of SOD1 in amyotrophic lateral sclerosis.Semantic proximity Read

Molecular mechanisms of excitotoxicity and their relevance to the pathogenesis of neurodegenerative diseases—an updateSemantic proximity Read

The role of hydrogen sulfide in aging and age-related pathologiesSemantic proximity Read

Therapeutic Potential of Heterocyclic Compounds Targeting Mitochondrial Calcium Homeostasis and Signaling in Alzheimer’s Disease and Parkinson’s DiseaseSemantic proximity Read

Sulforaphane - role in aging and neurodegenerationSemantic proximity Read