Article

Thrombolytic therapy based on lyophilized platelet-derived nanocarriers for ischemic stroke

2023-08-17

Abstract excerpt

<h4>Background: </h4> Intravenous administration of fibrinolytic drugs, such as recombinant tissue plasminogen activator (rtPA) is the standard treatment of acute thrombotic diseases. However, current fibrinolytics exhibit limited clinical efficacy because of their short plasma half-lives and risk of hemorrhagic transformations. Platelet membrane-based nanocarriers have received increasing attention for ischemic s...

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Literature Corpus work: 9296ea9f-9f07-54c2-ba55-6328fa0ae296
DOI: 10.21203/rs.3.rs-3251963/v1

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