Article

A strain-specific metabolic role for the UDP-glucose 4-epimerase Uge3 in <i>Aspergillus fumigatus</i> virulence

2026-06-17

Abstract excerpt

<h4>ABSTRACT</h4> Expression of a fungal-specific sub-telomeric gene, hrmA , in Aspergillus fumigatus is important for a colony biofilm morphology termed H-MORPH, increased hypoxic fitness, and virulence in a murine model of invasive pulmonary aspergillosis (IPA). How expression of hrmA contributes to virulence and worse disease progression is ill-defined. Increased hrmA expression results in reduced attachme...

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Literature Corpus work: 9260448e-eb8d-5385-ab17-5d780f5a93b4
DOI: 10.64898/2026.06.17.732805

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