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Within-host succession from an OXA-48-like to an NDM-type carbapenemase in clonal ST361 <i>Escherichia coli</i> recovered from sequential urinary and bloodstream infection

2026-07-30

Abstract excerpt

Carbapenem-resistant Escherichia coli (CREc) recovered sequentially from one patient typically retain the same carbapenemase, with escalating resistance usually attributed to porin loss combined with pre-existing β-lactamase expression. We used whole-genome sequencing to characterize a clonal pair of CREc isolates, CAEC145 and CAEC155, recovered 25 days apart from a hospitalized patient with sequential urinary an...

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Literature Corpus work
92502062-652a-5fd2-b2e3-f7ed44200711
DOI
10.64898/2026.07.27.741121
Open publication

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Within-host succession from an OXA-48-like to an NDM-type carbapenemase in clonal ST361 <i>Escherichia coli</i> recovered from sequential urinary and bloodstream infectionDOI 10.64898/2026.07.27.741121
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