Article

False-negative Molecular Diagnosis of SARS-CoV-2 in Samples with Amplification Inhibitors

2020-10-16

Abstract excerpt

Although rRT-PCR is the gold standard method for SARS-CoV-2 detection, some factors, such as amplification inhibitors presence, lead to false-negative results. Here we describe differences between rRT-PCR results for SARS-CoV-2 infection in normal and diluted samples, simulating the need for dilution due to amplification inhibitors presence. Viral RNA extraction of nasopharyngeal swabs samples from 20 patients pre...

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Literature Corpus work: 922613f3-c2bb-5972-97f3-632588c2b7d8
DOI: 10.20944/preprints202009.0450.v2

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