Article

Rapid clinical metagenomics enables early tailored therapy in complicated urinary tract infections and strengthens antimicrobial stewardship

2026-03-11

Abstract excerpt

Rapid and accurate diagnosis of UTIs remains difficult because culture-based methods are slow and less sensitive. This study evaluates URINN, a metagenomic workflow that detects uropathogens, antibiotic resistance genes, and virulence factors directly from patient urine samples. The optimized protocol was tested on a combined set of 349 clinical urine samples. URINN demonstrated 99% accuracy across all samples and...

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Identifiers and source

Literature Corpus work: 92239915-6c07-508b-96e1-67a98ceb70ba
DOI: 10.64898/2026.03.09.709250

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