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Metagenomic DNA sequencing for semi-quantitative pathogen detection from urine: a prospective, laboratory-based, proof-of-concept study

7 Jun 2022

Abstract excerpt

BACKGROUND: Semi-quantitative bacterial culture is the reference standard to diagnose urinary tract infection, but culture is time-consuming and can be unreliable if patients are receiving antibiotics. Metagenomics could increase diagnostic accuracy and speed by sequencing the microbiota and resistome directly from urine. We aimed to compare metagenomics to culture for semi-quantitative pathogen and resistome...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35688170
DOI: 10.1016/s2666-5247(22)00088-x

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