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Article

MRPL47 as a Novel Mitochondrial Biomarker for Early Detection and Therapeutic Response in Ovarian Cancer

2026-03-09

Abstract excerpt

MRPL47 (Mitochondrial Ribosomal Protein Large Subunit 47) gene in chromosome 3q26 encodes a protein that is part of the large subunit of the mitochondrial ribosome. We observed that MRPL47 is frequently amplified and overexpressed in ovarian cancer samples. Importantly, increased expression of MRPL47 mRNA is associated with high levels of MRPL47 protein in ovarian cancer patients. High expression of MRPL47 is als...

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Identifiers and source

Literature Corpus work
91e5a4b1-505c-5df5-bec8-03cb874e1382
DOI
10.64898/2026.03.05.709884
Open publication

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MRPL47 as a Novel Mitochondrial Biomarker for Early Detection and Therapeutic Response in Ovarian CancerDOI 10.64898/2026.03.05.709884
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