Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MRPS28 serves as a biomarker of diagnostic, prognostic, and immune modulation in pan-cancer and promotes breast cancer malignant phenotypes.

Frontiers in immunology - 1 Jan 2026

Guo Xiangdong, Wang Shixing, Lu Yunlong, Cai Rensang, Luo Zhifei, Hu Jiaying, Xue Fenggui, Niu Haiyan

Abstract excerpt

Background: MRPS28 (Mitochondrial Ribosomal Protein S28) belongs to the MRP family and plays a critical role in mitochondrial translation and cellular energy metabolism. However, the effect of MRPS28 in pan-cancer remains unknown. This study aimed to perform a comprehensive assessment of the oncogenic potential of MRPS28 in pan-cancer using several databases, with a particular focus on breast cancer. Methods: The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Movement

Share to Cell Proliferation

Share to DNA Methylation

Share to Gene Expression Regulation, Neoplastic

Share to Mitochondrial Proteins

Share to Ribosomal Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 41853286
DOI: 10.3389/fimmu.2026.1680772
PMCID: PMC12992041

Genes

MRPS28
MB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MRPS28 serves as a biomarker of diagnostic, prognostic, and immune modulation in pan-cancer and promotes breast cancer malignant phenotypes.PMID 41853286Read ↗

Mitochondrial ribosomal proteins: potential targets for cancer prognosis and therapySemantic proximity Read ↗

A novel biomarker, MRPS12 functions as a potential oncogene in ovarian cancer and is a promising prognostic candidateSemantic proximity Read ↗

Identification of the Upregulation of MRPL13 as a Novel Prognostic Marker Associated with Overall Survival Time and Immunotherapy Response in Breast Cancer.Semantic proximity Read ↗

A multidimensional analysis of MRPL17 protein in human tumorsSemantic proximity Read ↗

Expression and prognosis analysis of mitochondrial ribosomal protein family in breast cancerSemantic proximity Read ↗

MRPL13 Promotes Tumor Cell Proliferation, Migration and EMT Process in Breast Cancer Through the PI3K-AKT-mTOR PathwaySemantic proximity Read ↗

Pan-cancer analysis of the oncogenic effects of ribosomal protein L13 (MRPL13) and validation in hepatocellular carcinomaSemantic proximity Read ↗

MRPS23 is a novel prognostic biomarker and promotes glioma progression.Semantic proximity Read ↗

Overexpression of MRPL19 in predicting poor prognosis and promoting the development of lung adenocarcinomaSemantic proximity Read ↗

Comprehensive analysis of the large and small ribosomal proteins in breast cancer: Insights on proteomic and transcriptomic expression patterns, regulation, mutational landscape, and prognostic significance.Semantic proximity Read ↗

Mitochondrial ribosomal protein L3 (MRPL3): An early diagnostic biomarker and potential molecular target in pancreatic cancerSemantic proximity Read ↗

Comprehensive pan-cancer multi-omics analysis of PSMB7 reveals its prognostic significance and oncogenic role with experimental validation in lung and gastric cancersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.