Association between spironolactone use and COVID-19 outcomes in population-scale claims data: a retrospective cohort study

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Spironolactone has been proposed as a potential modulator of SARS-CoV-2 cellular entry. We aimed to measure the effect of spironolactone use on the risk of adverse outcomes following COVID-19 hospitalization. <h4>Methods</h4> We performed a retrospective cohort study of COVID-19 outcomes for patients with or without exposure to spironolactone, using population-scale claims dat...

Topics

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• COVID-19
• Estrogens
• Genome-Wide Association Study
• Gonadal Steroid Hormones
• Hospitalization
• Insulin-Like Growth Factor I
• Polymorphism, Single Nucleotide
• Testosterone

Identifiers and source

Literature Corpus work

913e851e-5224-51af-98ea-4ade6f81953b

DOI

10.1101/2023.02.28.23286515