Article

Accurate Imputation of Pathway-specific Gene Expression in Spatial Transcriptomics with PASTA

2025-03-27

Abstract excerpt

<title>Abstract</title> <p>Mapping the entire transcriptome at single-cell resolution under its natural spatial context is essential for investigating the oncogenesis and progression of diseases. The recently emerged targeted in-situ technologies retain the spatial organization of cells at high resolution, although they remain limited in the number of genes that can be simultaneously measured. To overcome this ob...

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Literature Corpus work: 9117c013-5d9d-5917-b703-8c0ec786c628
DOI: 10.21203/rs.3.rs-6255642/v1

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