Article

Preclinical Safety Evaluation of Human Lactoferrin Alpha (Effera <sup>®</sup> )

2026-06-01

Abstract excerpt

The preclinical safety of human-equivalent lactoferrin alpha (heqLFα; effera ® ), produced by Komagataella phaffii , was evaluated to support its use as a food ingredient in infant formula and products for young children. Genotoxicity was assessed using a bacterial reverse mutation (Ames) assay in five strains of Salmonella typhimurium and Escherichia coli, and an in vitro micronucleus assay in TK6 cells. Both...

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Literature Corpus work: 9090992c-8f5a-5870-ba76-7aaab457effd
DOI: 10.64898/2026.05.28.728516

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