Article

<i>Gl</i> Rac regulates an ATG8-independent autophagy-like pathway in <i>Giardia lamblia</i>

2026-02-19

Abstract excerpt

Autophagy is a conserved catabolic process essential for cellular homeostasis and adaptation to nutrient stress. The protozoan parasite Giardia lamblia lacks most canonical autophagy-related (ATG) genes, including the hallmark ATG8, raising longstanding questions about whether this deeply divergent parasite can perform autophagy. Here, we identify an ATG8-independent autophagy-like pathway in Giardia regulated b...

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Literature Corpus work: 9068d10a-1243-5e8b-ae07-8bfb7e5ec69a
DOI: 10.64898/2026.02.17.706457

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