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An RNA replicon vaccine encoding HA and NA prevents shedding of antigen- drifted 2009 pandemic H1N1 influenza virus in the pig model

2025-11-06

Abstract excerpt

<title>Abstract</title> <p> Seasonal influenza viruses escape the human immune response by antigenic drift, i.e. the positive selection of point mutations that prevent the binding of inhibitory antibodies to the influenza antigens HA and NA. The efficacy of seasonal influenza vaccines can be less than 50% if the selected influenza vaccine strain does not match the antigenic characteristics of the circulating sea...

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Literature Corpus work
90626a0f-51f7-5a82-8e4a-c8cea120b548
DOI
10.21203/rs.3.rs-7818522/v1
Open publication

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An RNA replicon vaccine encoding HA and NA prevents shedding of antigen- drifted 2009 pandemic H1N1 influenza virus in the pig modelDOI 10.21203/rs.3.rs-7818522/v1
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