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Article

Copy-number variants differ in frequency across genetic ancestry groups.

HGG advances - 10 Oct 2024

Schultz Laura M, Knighton Alexys, Huguet Guillaume, Saci Zohra, Jean-Louis Martineau, Mollon Josephine, Knowles Emma E M, Glahn David C, Jacquemont Sébastien, Almasy Laura

Abstract excerpt

Copy-number variants (CNVs) have been implicated in a variety of neuropsychiatric and cognitive phenotypes. We found that deleterious CNVs are less prevalent in non-European ancestry groups than they are in European ancestry groups of both the UK Biobank (UKBB) and a US replication cohort (SPARK). We also identified specific recurrent CNVs that consistently differ in frequency across ancestry groups in both the...

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Identifiers

PMID: 39138864
DOI: 10.1016/j.xhgg.2024.100340
PMCID: PMC11401192

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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