Article

Clinical characteristics and prenatal diagnosis for 22 families in Henan Province of China with X-linked agammaglobulinemia (XLA) related to Bruton’s tyrosine kinase (BTK) gene mutations.

2020-04-15

Abstract excerpt

<title>Abstract</title> <p>Background: X-linked agammaglobulinaemia (XLA) is a rare immunodeficiency disease for which recurrent severe infection is the major clinical symptom. BTK is the main causative gene, with X chromosome recessive inheritance. However, the mutations reported to date do not fully explain the disorder. <h4>Methods:</h4> We detected the percentage of CD19+ B cells and serum immunoglobulin (IgG...

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Literature Corpus work: 8f95ab18-aff3-5792-bc5a-c7b49742bb6e
DOI: 10.21203/rs.2.22278/v2

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