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Article

Prevalence of BTK mutations in male Algerian patterns with agammaglobulinemia and severe B cell lymphopenia.

Clinical immunology (Orlando, Fla.) - 1 Dec 2015

Boushaki Soraya, Tahiat Azzedine, Meddour Yanis, Chan Koon Wing, Chaib Samia, Benhalla Nafissa, Smati Leila, Bensenouci Abdellatif, Lau Yu-Lung, Magdinier Frédérique, Djidjik Réda

Abstract excerpt

X linked agammaglobulinemia (XLA) is the first described primary immunodeficiency and the most common form of agammaglobulinemia. It is characterized by susceptibility to recurrent infections, profound decrease of all immunoglobulin isotypes and very low level of B lymphocytes in peripheral blood. The disorder is caused by mutations in the Bruton's Tyrosine Kinase (BTK). Nine male patients suspected to have XLA...

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Identifiers

PMID: 26387629
DOI: 10.1016/j.clim.2015.09.011

Genes

BTK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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