Article

Chromatin-enriched RNAs mark active and repressive cis-regulation: an analysis of nuclear RNA-seq

2019-05-22

Abstract excerpt

Long noncoding RNAs ( lncRNAs ) localize in the cell nucleus and influence gene expression through a variety of molecular mechanisms. RNA sequencing of two biochemical fractions of nuclei reveals a unique class of lncRNAs, termed chromatin-enriched nuclear RNAs ( cheRNAs ) that are tightly bound to chromatin and putatively function to cis-activate gene expression. Until now, a rigorous analytic pipeline for nucl...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8f90b620-87ce-5026-bfa2-a2a3dfabbda8
DOI: 10.1101/646950

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Chromatin-enriched RNAs mark active and repressive cis-regulation: an analysis of nuclear RNA-seqDOI 10.1101/646950Read

eRNAkit: Expanding the Functional Atlas of human Enhancer RNAs Beyond the NucleusSemantic proximity Read

Studying RNA–DNA interactome by Red-C identifies noncoding RNAs associated with repressed chromatin compartment and reveals transcription dynamicsSemantic proximity Read

eRNA-IDO: a one-stop platform for identification, interactome discovery and functional annotation of enhancer RNAsSemantic proximity Read

RNA in unexpected places: long non-coding RNA functions in diverse cellular contexts.Semantic proximity Read

Beyond the Double Helix: Unraveling the Intricacies of DNA and RNA NetworksSemantic proximity Read

Genome-wide identification of stable RNA-chromatin interactionsSemantic proximity Read

Chromatin-associated intronic RNAs from long genes form introsomes that shape nuclear architecture in neuronal cellsSemantic proximity Read

Intergenic RNA mainly derives from nascent transcripts of known genesSemantic proximity Read

Long non-coding RNAs in nuclear bodies.Semantic proximity Read

Global mapping of RNA-chromatin contacts reveals a proximity-dominated connectivity model for ncRNA-gene interactionsSemantic proximity Read

Long Noncoding RNAs: At the Intersection of Cancer and Chromatin Biology.Semantic proximity Read

Widespread DNA off-targeting confounds studies of RNA chromatin occupancySemantic proximity Read