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Article

Protective heterologous T cell immunity in COVID-19 induced by MMR and Tdap vaccine antigens

2021-05-04

Abstract excerpt

<h4>ABSTRACT</h4> T cells are critical for control of viral infection and effective vaccination. We investigated whether prior Measles-Mumps-Rubella (MMR) or Tetanus-Diphtheria-pertussis (Tdap) vaccination elicit cross-reactive T cells that mitigate COVID-19. Using co-cultures of antigen presenting cells (APC) loaded with antigens and autologous T cells, we found a high correlation between responses to SARS-CoV-2...

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Identifiers and source

Literature Corpus work
8f44d7db-2c19-5060-afb9-59358ede749f
DOI
10.1101/2021.05.03.441323
Open publication

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