Article

Integrative proteogenomics for differential expression and splicing variation in a DM1 mouse model

2021-05-16

Abstract excerpt

Dysregulated mRNA splicing is involved in the pathogenesis of many diseases including cancer, neurodegenerative diseases, and muscular dystrophies such as myotonic dystrophy type 1 (DM1). Comprehensive assessment of dysregulated splicing on the transcriptome and proteome level has been methodologically challenging, and thus investigations have often been targeting only few genes. Here, we performed a large-scale c...

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Literature Corpus work: 8f143ccc-5630-596d-a24b-a16431666aa4
DOI: 10.1101/2021.05.15.443842

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