Article

A Potential Beta-hydroxybutyrate Therapy for Duchenne Muscular Dystrophy in Disease Models

2025-10-19

Abstract excerpt

Duchenne muscular dystrophy (DMD) is a common and lethal muscular degenerative disorder caused by mutations in the Dystrophin gene. Patients with DMD suffer progressive motor and respiratory decline over time and exhibit mitochondria defects at the cellular level, contributing to their reduced life expectancy. Despite extensive efforts, effective treatments for DMD remain unavailable. This study aims to explore a...

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Literature Corpus work: 3f39b4c8-6e0d-5ed3-b964-0d7466b31b91
DOI: 10.1101/2025.10.18.683257

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