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Specific activation of embryonic IFNAR1 and endometrial IFNAR2 induced by embryonic IFNτ directs normal uterine fate for bovine early implantation

2022-02-01

Abstract excerpt

<h4>Background: </h4> Interferon-tau (IFNτ), as an antiluteolytic factor secreted by trophoderm during the pregnancy of ruminants, actually functions by activating the IFNτ receptor 1 (IFNAR1) and IFNτ receptor 2 (IFNAR2). However, it has not been clearly understood how IFNτ-IFNAR cascade regulation processes between the embryo and uterine epithelial cells in ruminants. <h4>Methods: </h4>: CRISPR/Cas9 technology w...

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Literature Corpus work
8e9ca8b2-48e9-568f-9fe2-d3b5d7c6bf39
DOI
10.21203/rs.3.rs-1297654/v1
Open publication

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Specific activation of embryonic IFNAR1 and endometrial IFNAR2 induced by embryonic IFNτ directs normal uterine fate for bovine early implantationDOI 10.21203/rs.3.rs-1297654/v1
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