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Overexpression of the RNA-binding protein NrdA affects global gene expression and secondary metabolism in <i>Aspergillus</i> species

2021-03-16

Abstract excerpt

<h4>ABSTRACT</h4> RNA-binding protein Nrd1 plays a role in RNA polymerase II transcription termination. In this study, we showed that the orthologous NrdA is important in global mRNA expression and secondary metabolism in Aspergillus species. We constructed an nrdA conditional expression strain using the Tet-On system in Aspergillus luchuenesis mut. kawachii . Downregulation of nrdA caused a severe growth de...

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Literature Corpus work
8e6cb795-8097-5c59-8e93-016a830fa961
DOI
10.1101/2021.03.15.435561
Open publication

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Overexpression of the RNA-binding protein NrdA affects global gene expression and secondary metabolism in <i>Aspergillus</i> speciesDOI 10.1101/2021.03.15.435561
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